… of a multicenter, randomized, patients-blinded two-stage clinical trial on effects of endothelial function test in patients with non-obstructive coronary artery disease  …

H Liu, G Xie, W Huang, J Liu, N Zhao… - International Journal of …, 2021 - Elsevier
… is proof-of-concept clinical trial of a disruptive endothelial … adjunctive testing of peripheral
endothelial function will result … , and that these early aggressive endothelial function-guided …

[HTML][HTML] … relates with carotid intima-media thickness in atherosclerotic patients with normal renal function (eGFR≥ 60 mL/min/1.73 m2): a proof-of-concept study

J Donate-Correa, E Martín-Núñez… - Frontiers in …, 2023 - frontiersin.org
… expression protect against endothelial dysfunction in experimental … due to clinical
atherosclerotic vascular disease. … allowed us to show associations without definitive inferences …

… pressure but not Liraglutide-mediated weight loss improves early cardiovascular disease in obstructive sleep apnea: Data from a randomized proof-of-concept study.

C O'Donnell, S Crilly, A O'Mahony, B O'Riordan… - medRxiv, 2023 - medrxiv.org
… factors and endothelial function at baseline and end of study, … (CV) diseases, such as
coronary artery disease (CAD), … real-world studies revealed a significant association of CPAP …

[HTML][HTML] Cocoa flavanol consumption improves lower extremity endothelial function in healthy individuals and people with type 2 diabetes

M Bapir, GR Untracht, D Cooke, JH McVey… - Food & function, 2022 - pubs.rsc.org
… of lower extremity peripheral artery disease (PAD). Cocoa … on the association between
endothelial dysfunction as measured … proof-of-concept study were to assess if femoral artery (FA) …

[HTML][HTML] Efficacy and safety of the endothelin-1 receptor antagonist macitentan in epicardial and microvascular vasospasm; a proof-of-concept study

RGT Feenstra, TPJ Jansen, SM Boekholdt… - IJC Heart & …, 2023 - Elsevier
… , a small study in patients with coronary artery disease (n = 10… in endothelial function as
per rationale of the design of this … coronary arteries in collaboration with European society of …

Progress in aorta and peripheral cardiovascular disease research

, … on aorta and peripheral vascular diseases - … research, 2021 - academic.oup.com
… novel disease gene and provided proof-of-concept for a … Moreover, an independent genetic
association study in 506 FMD … pattern including severe endothelial injury associated with …

Nitrates in combination with hydralazine in cardiorenal syndrome: a randomized controlled proofofconcept study

SL Lim, M Gandhi, KL Woo, HR Chua, YC Lim… - ESC Heart …, 2020 - Wiley Online Library
… There is a high prevalence of endothelial dysfunction in our … Association Declaration of
Helsinki on ethics in medical … the form of peripheral vascular disease, chronic respiratory disease, …

Unraveling the pathophysiology of lower-limb postthrombotic syndrome in adolescents: a proof-of-concept study

ML Avila, RF Bentley, D Bastas, LR Brandão… - Blood …, 2023 - ashpublications.org
function is impaired in young patients with PTS underscores the relevance of developing
strategies to mitigate the effects of this chronic vascular disease … the association between each …

Short Term Effects of a Specific Music Therapy Intervention on Endothelial Function in Patients with Peripheral Arterial Disease (the Tarrega Trial Outcomes)

J De Haro, S Bleda - European Journal of Vascular and Endovascular …, 2019 - ejves.com
… The aim of this study was to assess the short-term efficacy of … upon the vascular reactivity and
endothelial function in healthy … Methods - The TARREGA clinical trial was a proof-of-concept

[HTML][HTML] Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies

A Daiber, S Chlopicki - Free Radical Biology and Medicine, 2020 - Elsevier
… and their relation to endothelial dysfunction and oxidative stress. … a clear link between
endothelial dysfunction and adverse redox … in the treatment of endothelial dysfunction and CVD. …